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Allergine


 Composition :
 
Each 1 gm Contains:  
- Diphenhydramine HCL 20 mg.
   
 Properties :
 
Allergine is antihistamines competitively inhibits histamine at H1 receptor. In addition; it also has substantial sedative, anticholinergic, antitussive, and antiemetic effects.
   
 Indications :
 
Allergine is indicated in the treatment of allergies, anaphylactic and inflammatory disease – urticaria, allergic dermatides and dermatoses, allergic conjunctivitis, drug and feed related allergies. Anaphylactic shock; aseptic total (diffuse) pododermatitis ( laminitis acuta), and chronic alveolar emphysema in horses; bronchial asthma, atony of forestomach and retained placenta in large and small ruminants; gangrenous mastitis in sheep; oedema disease; cases of insect and snake bites; transport disease; for anaesthesia of the nasal mucosa.
   
 Dosage and administration :
 
Administered by intramuscular injection, subcutaneouse or intravenous.

- Cattle : 0.5 – 1 mg active ingredient/kg per animal. IM or IV Injectable Solution Injectable Allergine Solutions
- Horses : 0.25 – 1 mg active ingredient/kg per animal. IV or IM.
- Dogs&Cats : 1 mg active ingredient/kg per animal three times daily. IM, SC, IV.
   
 Contraindications :
 
Diphenhydramine is contraindicated in patients with angle closure glaucoma, prostatic hypertrophy, pyloroduodenal or bladder neck obstruction, and COPD if mucosal secretion are a problem, hyperthyrodisim, cardiovascular disease or hypertension.
   
 Warnings :
 
-The most commonly seen adverse effect are CNS depression( lethargy, somnolence), and anticholinergic effects (dry mouth, urinary retention).

-The sedative effects of antihistamines may adversly affect the performance of working dogs.
   
 Withdrawal Period :
 
-Meat should not be used during treatment and within 24 hours from the last treatment.
-Milk should not be used during treatment and within 24 hours from the last treatment.
   
 Presentation :
 
50 ml.
   
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